Ok, cool. Thanks guys! So it boils down to boost the lead sound in some desired fashion and tell the FOH guy to incorporate that into his settings beforehand. That's cool and answers my (probably naive) question of whether the FOH should be reliable for this or the guitarist. I sometimes was told explicitly to NOT do that, but I can be confident in argumentation now, as it seems to be good practice.
Currently, I'm running an Engl Fireball, which effectively has 3 "settings" for me like clean, overdriven and some additional gain boost (you could have the boost on clean too, but doesn't matter for me). Physically just one channel with one eq section though. But I think I can go with that, as I like my lead tone with some added delay as it is now. It's just a matter of boosting gain a little bit then.