It depends on the music you´ll play on it. If you want a balls-out metal tone that never fails, with a tight chunky bottom end and above all, clarity, i´d go with EMGs, easily. 81s, 85s, 60s or whatever. Thats the main reason i use these pups; the super-solid bottom-end KLONG!!!! The mids and highs sound fine but that job could be done with just about any pickup. If you have to be more versatile for pop/rock/blues/covergigs i´d go with some low-, or medium-output DiMarzios/Duncans/Suhrs/whatever-else-thats-not-active and use some pedals for more gain if needed.